2019 Winners


Basic Research Award
Laura SOMMERVILLE, PhD
Duke University Medical Center, NC (US)
Understanding the effects of von Willebrand Factor deficiency on pericyte function during angiogenesis



Clinical Research Award
Simone MERLIN, PhD
University of Piemonte Orientale, Novara, Italy
Elucidating mechanisms of hemophilia A pediatric patients' pDCs in immune response to FVIII



2018 Winners


Basic Research Award
Jamie Marie O'SULLIVAN
Royal College of Surgeons, Dublin, Ireland
Unravelling the enigma of von Willebrand Factor (VWF) clearance; Characterization of a novel VWF clearance receptor





2017 Winners


Basic Research Award
Manjunath GOOLYAM BASAVARAJ
The Children's Hospital of Philadelphia, Philadelphia, US
Novel strategies to enhance factor X (FX) activation through improved factor VIIIa (FVIIIa) cofactor activity and stability



Clinical Research Award
Paul BATTY
Queen Mary University of London, London, UK 
High-Throughput Amino Acid Sequence Epitope Mapping of Inhibitory Antibodies in Non-Severe and Acquired Haemophilia A



2016 Winners


Basic Research Prize
Name: Nimesh GUPTA
Original Work: "Regulation of immune responses to protein therapeutics by transplacental induction of T cell tolerance"
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/25696000

Clinical Research Prize
Names: Davide MATINO
Original Work: "IDO1 suppresses inhibitor development in hemophilia A treated with factor VIII"
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/26426076


2015 Winners


Basic Research Prize
Name: Giulia PAVANI
Original Work: "The endothelial protein C receptor enhances hemostasis of FVIIa administration in hemophilic mice in vivo"
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/24957146

Clinical Research Prize
Names: Jörg KAHLE
Original Work: "Epitope mapping via selection of anti-FVIII antibody-specific phagepresented peptide ligands that mimic the antibody binding sites."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/25520269


2014 Winners


Basic Research Prize
Name: Federico MINGOZZI
Original Work: "Overcoming Preexisting Humoral Immunity to AAV Using Capsid Decoys."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/23863832

Clinical Research Prize
Names: Yohann REPESSÉ and Ivan PEYRON
Original Work: "Development of inhibitory antibodies to therapeutic factor VIII in severe hemophilia A is associated with microsatellite polymorphisms in the HMOX1 promoter."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/23716558


2013 Winners


1st Prize
Name: Qizhen SHI
Original Work: "Factor VIII inhibitors: von Willebrand factor makes a difference in vitro and in vivo."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/22908929

2nd Prize
Name:  Ana Maria NAVARRETE
Original Work: "A murine model to characterize the antithrombotic effect of molecules targeting human von Willebrand factor."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/22915646

3rd Prize
Name: Carolyn MILLAR
Original Work: "Characterisation of von Willebrand factor A1 domain mutants I1416N and I1416T: correlation of clinical phenotype with flow-based platelet adhesion."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/22537243


2012 Winners


1st Prize
Name: Rodney M. CAMIRE and Lacramioara IVANCIU
Original Work: "A zymogen-like factor Xa variant corrects the coagulation defect in hemophilia."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/22020385

2nd Prize
Name: Rezan KADIR
Original Work: "Noninvasive prenatal diagnosis of hemophilia by microfluidics digital PCR analysis of maternal plasma DNA."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/21263151

3rd Prize
Name: Katherine A. HIGH
Original Work: "In vivo genome editing restores haemostasis in a mouse model of haemophilia."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/21706032


2011 Winners


1st Prize
Name: Bernd ENGELMANN and Steffen MASSBERG
Original Work: "Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/20676107

2nd Prize
Name:  Jonathan FINN
Original Work: "Eradication of neutralizing antibodies to factor VIII in canine hemophilia A after liver gene therapy."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/20876851

3rd Prize
Name: Reinhard SCHNEPPENHEIM
Original Work: "A cluster of mutations in the D3 domain of von Willebrand factor correlates with a distinct subgroup of von Willebrand disease: type 2A/IIE."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/20351307


2010 Winners


1st Prize
Name: Augusto B. FEDERICI
Original Work: "Clinical and molecular predictors of thrombocytopenia and risk of bleeding in patients with von Willebrand disease type 2B: a cohort study of 67 patients."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/18805962

2nd Prize
Name:  José Manuel SORIA FERNÁNDEZ
Original Work: "Identification of ZNF366 and PTPRD as novel determinants of plasma homocysteine in a family-based genome-wide association study."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/19525478

3rd Prize
Name: Antonio COPPOLA
Original Work: "Factor VIII gene (F8) mutations as predictors of outcome in immune tolerance induction of hemophilia A patients with high-responding inhibitors"
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/19740093


2009 Winners


1st Prize
Name: Giancarlo CASTAMAN
Original Work: "Response to desmopressin is influenced by the genotype and phenotype in type 1 von Willebrand disease (VWD): results from the European Study MCMDM-1VWD."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/18230755

2nd Prize
Name:  Eduardo TIZZANO
Original Work: "Identification of 31 novel mutations in the F8 gene in Spanish hemophilia A patients: structural analysis of 20 missense mutations suggests new intermolecular binding sites."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/18184865

3rd Prize
Name: Carlos Daniel DE BRASI
Original Work: "Developing a new generation of tests for genotyping hemophilia-causative rearrangements involving int22h and int1h hotspots in the factor VIII gene."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/18284600


2008 Winners


1st Prize
Name: Javier CORRAL
Original Work: "Antithrombin Cambridge II (A384S): an underestimated genetic risk factor for venous thrombosis."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/17244682

2nd Prize
Name:  Irene LÓPEZ VILCHEZ
Original Work: "Tissue factor-enriched vesicles are taken up by platelets and induce platelet aggregation in the presence of factor VIIa."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/17264948

3rd Prize
Name: Andra JAMES
Original Work: "Bleeding events and other complications during pregnancy and childbirth in women with von Willebrand disease."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/17403089