2017 Winners


Basic Research Prize
Manjunath GOOLYAM BASAVARAJ
The Children's Hospital of Philadelphia, Philadelphia, US
Novel strategies to enhance factor X (FX) activation through improved factor VIIIa (FVIIIa) cofactor activity and stability



Clinical Research Prize
Paul BATTY
Queen Mary University of London, London, UK 
High-Throughput Amino Acid Sequence Epitope Mapping of Inhibitory Antibodies in Non-Severe and Acquired Haemophilia A



2016 Winners


Basic Research Prize
Name: Nimesh GUPTA
Original Work: "Regulation of immune responses to protein therapeutics by transplacental induction of T cell tolerance"
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/25696000

Clinical Research Prize
Names: Davide MATINO
Original Work: "IDO1 suppresses inhibitor development in hemophilia A treated with factor VIII"
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/26426076


2015 Winners


Basic Research Prize
Name: Giulia PAVANI
Original Work: "The endothelial protein C receptor enhances hemostasis of FVIIa administration in hemophilic mice in vivo"
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/24957146

Clinical Research Prize
Names: Jörg KAHLE
Original Work: "Epitope mapping via selection of anti-FVIII antibody-specific phagepresented peptide ligands that mimic the antibody binding sites."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/25520269


2014 Winners


Basic Research Prize
Name: Federico MINGOZZI
Original Work: "Overcoming Preexisting Humoral Immunity to AAV Using Capsid Decoys."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/23863832

Clinical Research Prize
Names: Yohann REPESSÉ and Ivan PEYRON
Original Work: "Development of inhibitory antibodies to therapeutic factor VIII in severe hemophilia A is associated with microsatellite polymorphisms in the HMOX1 promoter."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/23716558


2013 Winners


1st Prize
Name: Qizhen SHI
Original Work: "Factor VIII inhibitors: von Willebrand factor makes a difference in vitro and in vivo."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/22908929

2nd Prize
Name:  Ana Maria NAVARRETE
Original Work: "A murine model to characterize the antithrombotic effect of molecules targeting human von Willebrand factor."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/22915646

3rd Prize
Name: Carolyn MILLAR
Original Work: "Characterisation of von Willebrand factor A1 domain mutants I1416N and I1416T: correlation of clinical phenotype with flow-based platelet adhesion."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/22537243


2012 Winners


1st Prize
Name: Rodney M. CAMIRE and Lacramioara IVANCIU
Original Work: "A zymogen-like factor Xa variant corrects the coagulation defect in hemophilia."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/22020385

2nd Prize
Name: Rezan KADIR
Original Work: "Noninvasive prenatal diagnosis of hemophilia by microfluidics digital PCR analysis of maternal plasma DNA."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/21263151

3rd Prize
Name: Katherine A. HIGH
Original Work: "In vivo genome editing restores haemostasis in a mouse model of haemophilia."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/21706032


2011 Winners


1st Prize
Name: Bernd ENGELMANN and Steffen MASSBERG
Original Work: "Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/20676107

2nd Prize
Name:  Jonathan FINN
Original Work: "Eradication of neutralizing antibodies to factor VIII in canine hemophilia A after liver gene therapy."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/20876851

3rd Prize
Name: Reinhard SCHNEPPENHEIM
Original Work: "A cluster of mutations in the D3 domain of von Willebrand factor correlates with a distinct subgroup of von Willebrand disease: type 2A/IIE."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/20351307


2010 Winners


1st Prize
Name: Augusto B. FEDERICI
Original Work: "Clinical and molecular predictors of thrombocytopenia and risk of bleeding in patients with von Willebrand disease type 2B: a cohort study of 67 patients."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/18805962

2nd Prize
Name:  José Manuel SORIA FERNÁNDEZ
Original Work: "Identification of ZNF366 and PTPRD as novel determinants of plasma homocysteine in a family-based genome-wide association study."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/19525478

3rd Prize
Name: Antonio COPPOLA
Original Work: "Factor VIII gene (F8) mutations as predictors of outcome in immune tolerance induction of hemophilia A patients with high-responding inhibitors"
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/19740093


2009 Winners


1st Prize
Name: Giancarlo CASTAMAN
Original Work: "Response to desmopressin is influenced by the genotype and phenotype in type 1 von Willebrand disease (VWD): results from the European Study MCMDM-1VWD."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/18230755

2nd Prize
Name:  Eduardo TIZZANO
Original Work: "Identification of 31 novel mutations in the F8 gene in Spanish hemophilia A patients: structural analysis of 20 missense mutations suggests new intermolecular binding sites."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/18184865

3rd Prize
Name: Carlos Daniel DE BRASI
Original Work: "Developing a new generation of tests for genotyping hemophilia-causative rearrangements involving int22h and int1h hotspots in the factor VIII gene."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/18284600


2008 Winners


1st Prize
Name: Javier CORRAL
Original Work: "Antithrombin Cambridge II (A384S): an underestimated genetic risk factor for venous thrombosis."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/17244682

2nd Prize
Name:  Irene LÓPEZ VILCHEZ
Original Work: "Tissue factor-enriched vesicles are taken up by platelets and induce platelet aggregation in the presence of factor VIIa."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/17264948

3rd Prize
Name: Andra JAMES
Original Work: "Bleeding events and other complications during pregnancy and childbirth in women with von Willebrand disease."
Pubmed Website: http://www.ncbi.nlm.nih.gov/pubmed/17403089